ethyl β-oxo-4-(trifluoromethyl)-benzenepropanoic acid
3-Oxo-3-(4-Trifluoromethylphenyl)Propionic Acid Ethyl Ester
CAS: 106263-53-0
Molecular Formula: C12H11F3O3
ethyl β-oxo-4-(trifluoromethyl)-benzenepropanoic acid - Names and Identifiers
ethyl β-oxo-4-(trifluoromethyl)-benzenepropanoic acid - Physico-chemical Properties
| Molecular Formula | C12H11F3O3 |
| Molar Mass | 260.21 |
| Density | 1.270g/mLat 25°C(lit.) |
| Boling Point | 248-249°C(lit.) |
| Flash Point | >230°F |
| Vapor Presure | 0.00164mmHg at 25°C |
| pKa | 9.09±0.25(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.4880(lit.) |
| Physical and Chemical Properties | WGK Germany:3 |
ethyl β-oxo-4-(trifluoromethyl)-benzenepropanoic acid - Risk and Safety
| Hazard Symbols | F - Flammable |
| WGK Germany | 3 |
ethyl β-oxo-4-(trifluoromethyl)-benzenepropanoic acid - Introduction
Ethyl 3-carbonyl -3-(4-trifluoromethylphenyl) propionate (abbreviated as TFMAE) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Molecular formula: C12H11F3O3
-Molecular weight: 270.21g/mol
-Melting point:-25°C
-Boiling Point: 175-176°C
-Density: 1.333 g/mL
-Solubility: can be dissolved in organic solvents such as ether, alcohol and ester
Use:
- TFMAE is often used as an intermediate in organic synthesis to prepare other compounds.
-It can be used as a solvent and catalyst for chemical reactions to promote the reaction.
- TFMAE can also be used as a surfactant, wetting agent and emulsifier.
Preparation Method:
-The preparation method of TFMAE is usually realized by esterification reaction, that is, 3-hydroxy-3-(4-trifluoromethylphenyl) propionic acid and ethanol are esterified to generate TFMAE.
Safety Information:
-The use of TFMAE should follow laboratory safety practices, including the wearing of appropriate personal protective equipment such as gloves and safety glasses.
-It may be irritating to skin, eyes and mucous membranes, please avoid direct contact.
-Avoid contact with ignition or high temperature during storage and handling to prevent burning or explosion.
-Inhalation or ingestion of large quantities may be harmful to health. If an accident occurs, please seek medical attention immediately.
Nature:
-Appearance: colorless liquid
-Molecular formula: C12H11F3O3
-Molecular weight: 270.21g/mol
-Melting point:-25°C
-Boiling Point: 175-176°C
-Density: 1.333 g/mL
-Solubility: can be dissolved in organic solvents such as ether, alcohol and ester
Use:
- TFMAE is often used as an intermediate in organic synthesis to prepare other compounds.
-It can be used as a solvent and catalyst for chemical reactions to promote the reaction.
- TFMAE can also be used as a surfactant, wetting agent and emulsifier.
Preparation Method:
-The preparation method of TFMAE is usually realized by esterification reaction, that is, 3-hydroxy-3-(4-trifluoromethylphenyl) propionic acid and ethanol are esterified to generate TFMAE.
Safety Information:
-The use of TFMAE should follow laboratory safety practices, including the wearing of appropriate personal protective equipment such as gloves and safety glasses.
-It may be irritating to skin, eyes and mucous membranes, please avoid direct contact.
-Avoid contact with ignition or high temperature during storage and handling to prevent burning or explosion.
-Inhalation or ingestion of large quantities may be harmful to health. If an accident occurs, please seek medical attention immediately.
Last Update：2024-04-10 22:29:15
